From Mental Floss:
I’ll try to put this as delicately as I can. Apparently there’s a significant debate about whether it’s better to fold several sheets of paper, or crumple them together in a bunch. One major argument in favor of the “fold” method is that depending on the quality of your paper and your folding technique, you can refold (and thus reuse) a single set of sheets. The counter-argument is that this is super-gross. I have my own opinions on this issue, but let’s just say I’ve tried multiple methodologies over the years and feel that I’ve perfected my technique.
Of the 25,100 people participating in the survey, 72% are folders and 27% are crumplers.
Hmmmm, that leaves 1%. Maybe they don’t use tissue.